Endocrine Abstracts

Background: Nottingham University Hospitals (NUH) has a joint endocrine/antenatal clinic to manage autoimmune hyperthyroidism in pregnancy, with the aim of close monitoring and management.Aim: To review service according to NUH standards (Pregnant Women with Thyroid Dysfunction):1. At 20 weeks if thyrotoxic/on antithyroid drugs (ATD)/post radio-iodine or surgery, check thyrotropin receptor autoantibodies (TSHRAb).<p class="abst...

In May 2011 a 55-year-old South East Asian man had a tumour removed from the floor of his mouth. The histology was consistent with a brown tumour of hyperparathyroidism. His PTH was raised at 12.3 pmol/l (NR 1.6–7.5) and he was referred to the endocrinology clinic. His serum calcium was 2.22 mmol/l (NR 2.2–2.6 mmol/l) and his serum 25 (OH) vitamin D level was <15 (NR >50 nmol/l) with a normal alkaline phosphatase. He had no symptoms of osteomalacia. He is a v...

A 52-year-old man was referred in June 2009 with weakness, unsteadiness, diarrhoea and weight loss of 14 kg in the last 4 months. His past medical history included hypertension, ischaemic heart disease and chronic obstructive pulmonary disease. He was a heavy smoker and admitted to drinking heavily for the past 9 months. His serum sodium was 126 mmol/l, serum potassium 2.0 mmol/l, serum bicarbonate 31 mmol/l. His chest X-ray was normal. He had had persistent hypokalaemia for 4...